Isabel Bartles grew up in New York City, Stuttgart, Germany, and Cookeville, Tennessee. She holds a Bachelor of Arts in Music from the University of Mississippi, a Master of Music in Violin Performance from Louisiana State University, and has done further study in Tel Aviv, Israel with Yair Kless. She has participated in master classes with Dorothy Delay and Max Rostal.
Formerly, she taught at the Stuttgarter Musikschule (Germany), the Voelser Musikschule (Austria), and Blair School of Music, Vanderbilt University. In addition to playing recital and chamber music concerts on three continents, she has been soloist with the Staedtische Orchester Kornwestheim, Corinth Symphony Orchestra, and the University of Missippi Orchestra among others.
She is a member of the Nashville Symphony Orchestra, and has also been a member of the Innsbrucker Symphonieorchester (Austria), the Herzliya Chamber Orchetra (Israel), and Vox Artis (Finland). She plays an instrument built by Enrico Orselli in 1910.